Enterprise Console using lots of CPU and not functional anymore

I can't pinpoint why this is happening all of a sudden, but navigating the EC and trying to do anything just hangs for long periods of time or just hangs period. We use an external MS-SQL database. Running DebugView i see lots of this:

[2220] log4net:ERROR [RollingFileAppender] Unable to acquire lock on file C:\Users\daNduda\AppData\Local\Sophos\Sophos Endpoint Management\5.0\log\sophos-ui-framework.log. The process cannot access the file 'C:\Users\daNduda\AppData\Local\Sophos\Sophos Endpoint Management\5.0\log\sophos-ui-framework.log' because it is being used by another process. [2220] [2220] *** HR originated: -2147024774[2220] ***   Source File: d:\iso_whid\x86fre\base\isolation\com\copyout.cpp, line 1302[2220] [2220] [2220] *** HR propagated: -2147024774[2220] ***   Source File: d:\iso_whid\x86fre\base\isolation\com\enumidentityattribute.cpp, line 144[2220] [2220] [2220] *** HR originated: -2147024774[2220] ***   Source File: d:\iso_whid\x86fre\base\isolation\com\copyout.cpp, line 1302[2220] [2220] [2220] *** HR propagated: -2147024774[2220] ***   Source File: d:\iso_whid\x86fre\base\isolation\com\enumidentityattribute.cpp, line 144[2220] [1324] 1324: 2012-05-15 10:40:33.629 [CBS]                       IsCacheStillGood: True. [1324] 1324: 2012-05-15 10:42:35.813 [CBS]                       IsCacheStillGood: True. [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] Trace Start:0End Index:28 [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] Trace Start:0End Index:28 [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] Trace Start:0End Index:28 [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] Trace Start:0End Index:28 [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] Trace Start:0End Index:28 [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] Trace Start:0End Index:28 [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] RenderEventToBuffer failed because of insufficient memory.-122-The data area passed to a system call is too small [1324] 1324: 2012-05-15 10:44:36.448 [CBS]                       IsCacheStillGood: True. [2220] Warning     [0x000013E0] This group was not constructed from the group heirachy tree, it will be slower [2220] Warning     [0x000013E0] This group was not constructed from the group heirachy tree, it will be slower [1324] 1324: 2012-05-15 10:46:37.140 [CBS]                       IsCacheStillGood: True. [1324] 1324: 2012-05-15 10:48:37.972 [CBS]                       IsCacheStillGood: True. [1324] 1324: 2012-05-15 10:50:38.598 [CBS]                       IsCacheStillGood: True.