Block specific file from being opened?

Hi All, 

Is it possible to set up an "on access" scan for a file we have defined ourselves?

We currently use data control to restrict access to the file if it is copied to a browser/mail client but would like to prevent the file being opened.

Is it possible somehow?

I can see you can add specific files to the exclusion list for suspicious files but it doesn't pick them up or report on them.

Even being able to add the file as an exclusion and then report on it would be fine.

Any ideas?

Thanks,

P