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Transport endpoint is not connected

System: ASG 7.400

After upgrading to 7.400 (from 7.306), the site
  http://esupport.trendmicro.com/support/enterprise/search.aspx
cannot be accessed any longer.
I have do admit, that I don't know, if it worked before the upgrade.
Without proxy, it's doing fine.

Error:
2009:02:27-08:13:39 proxy httpproxy[4910]: id="0002" severity="info" sys="SecureWeb" sub="http" name="web request blocked" action="block" method="GET" srcip="172.16.1.5" user="" statuscode="502" cached="0" profile="REF_BkQOuXyPbv (General)" filteraction="REF_DefaultHTTPCFFAction (Default content filter action)" size="2215" time="1331 ms" request="0xb2c43108" url="esupport.trendmicro.com/.../search.aspx" exceptions="av,auth,content,url,mime" error="Transport endpoint is not connected"

As you can see, most of the checks are already skipped ....
Any Idea what that message means?

Kind regards,
Tom


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