I have a hyper-v server with several .vhdx drives for virtual machines.
Is Sophos Endpoint safe to run on the host machine without corrupting the .vhdx files?
http://social.technet.microsoft.com/wiki/contents/articles/2179.hyper-v-anti-virus-exclusions-for-hyper-v-hosts.aspx
Shows an exclusion list
If you choose to run programs in the management operating system, you should also run your antivirus solution there and add the following to the antivirus exclusions to avoid negative performance impacts to all Virtual Machines running on that host:
All folders containing VHD, VHDX, AVHD, AVHDX, VSV and ISO files
Default virtual machine configuration directory, if used C:\ProgramData\Microsoft\Windows\Hyper-V
Default snapshot files directory, if used %systemdrive%\ProgramData\Microsoft\Windows\Hyper-V\Snapshots
Custom virtual machine configuration directories, if applicable
Virtual machine virtual hard disk files directory. By default, it is C:\Users\Public\Documents\Hyper-V\Virtual Hard Disks.
Custom virtual hard disk drive directories
Snapshot files directory. By default, it is %systemdrive%\ProgramData\Microsoft\Windows\Hyper-V\Snapshots.
Vmms.exe (Note: May need to be configured as process exclusions within the antivirus software)
Vmwp.exe (Note: May need to be configured as process exclusions within the antivirus software)
Additionally, when you use Cluster Shared Volumes, exclude the CSV path C:\ClusterStorage and all its subdirectories.
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