CTO, Convergent Information Security Solutions, LLC
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It happens to me once in a while on Windows 8 64-bit and 32-bit. What I do is open the options (button there in Action Center) and tell it to enable Sophos on both AV and Spyware even though Sophos appears to be on and running. After a few minutes, Windows stops being stupid and turns back into 'I think I can' and the errors don't show until the next time.
XG 19.5 GA 64-bit | Intel Xeon 4-core v3 1225 3.20Ghz
16GB Memory | 500GB SSD HDD | GB Ethernet x5