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Logins to Office365 keep failing

I have found for the last few weeks/months that I consistently have problems logging into Office365. The only place I have this problem is on my LAN behind my Sophos UTM 9. To be clear, this isn't a matter of incorrect passwords!

Login attempts are successful around 20% of the time. The other 80% the page waits and waits and eventually give me an error:

- In the bottom Chrome status bar I see "Waiting for https://outlook.office365.com/". This will keep going for approx 30-40 seconds and then I get a page saying

The outlook.office.com page isn’t working

outlook.office.com didn’t send any data.

ERR_EMPTY_RESPONSE
It doesn't seem to matter what browser I use (even Microsoft IE or Edge). I've tried googling for this but I've not really come up with anything. I'm suspicious it's something to do with the Sophos firewall and ports. I think I read somewhere something about Office365 requests needing to open additional ports, though why it works sometimes and not others I have no idea, and would this even be true for browser-based Office365?
Does anyone else have this problem? What can I do to fix it? Or troubleshoot it?


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