There are a number of threads on the site commenting on the need to turn off virus scanning for the IOS devices and YouTube, and there is even a built-in exception for googlevideo.com. However, this does not seem to be adequate.To make this work better you need to add an additional URL exception for youtube.com as well.
You can add another URL by copying the googlevideo URL and changing the googlevideo to youtube. This will allow YouTube to work for IOS devices (at least this worked for our network).
Mike
Update: If you are on Comcast, it appears they are doing some caching of YouTube content. It turns out that the URL they are using has a "-" in it, so the rule will need to be modified to accommodate this. Just add a - to the end of the pattern which would give you something like this:
^http://[A-Za-z0-9.-]+\.youtube\.com/videoplayback
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