Hello guys
After my epic fail from yesterday (https://community.sophos.com/products/unified-threat-management/astaroorg/f/110/t/71145), i still don't got my mail system to work again. No inbound and no outbound mails ar working.
finally found a workaround for this issue by disabling the "Scan relayed (outgoing) messages" checkbox. Interesting, also the inbound email startet to work again after disabling this option.