SAV Message: No valid temporary directory

A users computer is reporting some error messages that I don't quite understand.  Sophos and google searches have failed me thus far.  I don't think it's urgent, but as it's occuring on a VIP, best to check out.

Any thoughts?

Thanks

Jon

User: AD\VIPuser
Scan: On-access
Machine: S38054

Scanning "C:\Users\VIPuser\AppData\Local\Microsoft\Windows\Temporary Internet Files\Low\Content.IE5\5MQ64TW6\WAforColleagueFinance_-_20121113[1].pdf" returned SAV Interface error 0x2004021f: No valid temporary directory found.

Scanning "C:\Users\VIPuser\AppData\Local\Microsoft\Windows\Temporary Internet Files\Low\Content.IE5\5MQ64TW6\WAforColleagueFinance_-_20121113[1].pdf" returned SAV Interface error 0x2004021f: No valid temporary directory found.

Scanning "C:\Users\VIPuser\AppData\Local\Microsoft\Windows\Temporary Internet Files\Low\Content.IE5\5MQ64TW6\WAforColleagueFinance_-_20121113[1].pdf" returned SAV Interface error 0x2004021f: No valid temporary directory found.

Scanning "C:\Users\VIPuser\AppData\Local\Microsoft\Windows\Temporary Internet Files\Low\Content.IE5\5MQ64TW6\WAforColleagueFinance_-_20121113[1].pdf" returned SAV Interface error 0x2004021f: No valid temporary directory found.

Scanning "C:\Users\VIPuser\AppData\Local\Microsoft\Windows\Temporary Internet Files\Low\Content.IE5\5MQ64TW6\WAforColleagueFinance_-_20121113[1].pdf" returned SAV Interface error 0x2004021f: No valid temporary directory found.

Scanning "C:\Users\VIPuser\AppData\Local\Microsoft\Windows\Temporary Internet Files\Low\Content.IE5\5MQ64TW6\WAforColleagueFinance_-_20121113[1].pdf" returned SAV Interface error 0x2004021f: No valid temporary directory found.

Scanning "C:\Users\VIPuser\AppData\Local\Microsoft\Windows\Temporary Internet Files\Low\Content.IE5\5MQ64TW6\WAforColleagueFinance_-_20121113[1].pdf" returned SAV Interface error 0xa004021c: Invalid return code from SAV Interface client callback function.