Protect client computer failed "waiting for response from computer"

Hi there,

I'm a newer, and I'm using Sophos Enterprise Console to protect the client computer.  Enterprise Console version is 4.7..., and the version of  EndPoint antivirus I'm planing to setup to client computer is 10.0. 

When I protect the client computer, I can choose "FireWall", "Compliance Control", "Patch" and "Third-Party security software detection".   Except the "Compliance Control" I choosed the other three, and the client computer can be reached, but after a little while, there will be an error:" Waiting for response from computer".

Does anyone know this reason?

Thanks  a lot.