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Can't remove Mal/Iframe-F from Macintosh running 10.5.8

Please excuse me if this has been discussed before, but I seem to be unable to identify or remove the source of a Mal/Iframe-F virus that has infected by iMac that is running OS 10.5.8.

I regularly receive the same set of messages concerning an infected .mp3, .ppt, files, which appears briefly when I open the Quarantine Manager.  I am also running ClamXav which is instructed to delete all infected files (they are moved to my trashbin; all files show 0 bits in trash).  ClamXav is also identifying a large number of infected Apple Mail files and moving them to the trash bin. 

Once I have opened the Quarantine window in SOPHOS, the items listed disappear (this may be due to what ClamXav is doing).  I would like to end this virus, but would like some stepwise advice on what I should do to eradicate the source problem.  Any help would be greatly appreciated.

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  • You are likely experiencing one of the symptoms of having multiple AV solutions installed at the same time... however, Mal/iFrame-F is generally found in web pages, not email attachments.  Likely you are continually visiting a site that contains a hidden malicious iFrame, and the html is cached in your web cache.  When the cache clears, the infection vanishes from quarantine.  The next time you load the page, the infection is re-cached, causing a new detection.

    :1004899
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  • You are likely experiencing one of the symptoms of having multiple AV solutions installed at the same time... however, Mal/iFrame-F is generally found in web pages, not email attachments.  Likely you are continually visiting a site that contains a hidden malicious iFrame, and the html is cached in your web cache.  When the cache clears, the infection vanishes from quarantine.  The next time you load the page, the infection is re-cached, causing a new detection.

    :1004899
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