Running Mountain Lion OS X 10.8.3 (12D78) on new IMac, installed Sophos and scheduled a daily scan at 4:00AM.
I have tried a few times, but each time I bring my mac out of sleep at 8 in the morning the Sophos Scan starts then, it has not been running since 4:00AM as when I look at the progress its only 1% complete, meaning by me activating the mac it has started the scan.
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