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Sophos interfering with iPad IOS update?

I recently tried to upgrade my iPad to the latest version of IOS.  Although the file loaded onto my Mac, the load onto the iPad seems to have failed with the iPad now stuck in recovery mode. Itunes reports an "unknown error 21". 

According to Apple support, the most likely cause of this error is third party security software.  

I am on OSX 10.8.2, itunes 11.0.2(26) and am trying to upgrade to the latest IOS level.

The host machine is a Macbook Pro, the iPad is an iPad 2.

Questions:

1. is anyone  aware of/experiencing this problem?

2. Switching off on access scanning had no effect. How do I disable the Mac antivirus software temporarily, to try and rule it out as the source of the problem? 

thanks,

L.O.

:1011608


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