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Quarantine Manager won't complete clean up

I installed Sophos for Mac 8.0.9c recently on my Mac running OS 10.7.5. I did a full scan today - Mal/ASFDldr-A was detected. I followed the steps to clean up - the quarantine manager has been running over 2 hours displaying the "clean up threats..." dialogue box. I can't stop this process. I am unable to turn off, or log out of, my computer. Will the clean up eventually complete? If it is frozen in this mode, how do I get control of my computer back? Thanks

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