Apple has posted a warning here that "Sophos Anti-Virus on-access scanner versions 8.0 - 9.1 may cause OS X Mavericks to unexpectedly restart (kernel panic)." Since that has never happened to me, I was surprised to see this. And it sounds like the solution offered is surgery on the Sophos AV installation.
BTW, how does one get Sophos AV 9.1?
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