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No. That is AV. Decryption would be the points on the right or the TLS/SSL Rules on the same page. 

But again, thats only one of multiple factos, which can break your application. I would assume, you should look deeper or contact a Sophos Partner to get the configuration done. 

 the SSL/TLS is off 

Then you have a fundamental issue within your Setup, which needs to be checked by a Sophos Partner. There seems to be something broken in your network.